The lysine deacetylase Sirtuin 1 modulates the localization and function of the Notch1 receptor in regulatory T cells

Some interesting fact of my work The ability to tune cellular functions in response to nutrient availability has important consequences for immune homeostasis. The activity of the receptor Notch in regulatory T (Treg) cells, which suppress the functions of effector T cells, is indispensable for Treg cell survival under conditions of diminished nutrient supply. Antiapoptotic signaling induced… Read More The lysine deacetylase Sirtuin 1 modulates the localization and function of the Notch1 receptor in regulatory T cells